Spinach Artichoke Grilled Cheese

Featured in: Family Dinners

This spinach artichoke grilled cheese combines creamy mozzarella, fresh spinach, and tender artichoke hearts between perfectly toasted sourdough slices. Sauté the spinach until wilted, mix with artichoke hearts, cream cheese, and Parmesan, then spread onto bread and cook until golden and melted.

The result is a sophisticated comfort sandwich that's vegetarian-friendly and ready in just 25 minutes. Serve alongside tomato soup for a classic pairing.

Updated on Sun, 18 Jan 2026 12:58:00 GMT
Golden-brown Spinach Artichoke Grilled Cheese on sourdough oozing melted mozzarella and creamy filling. Save
Golden-brown Spinach Artichoke Grilled Cheese on sourdough oozing melted mozzarella and creamy filling. | turbobaker.com

My neighbor knocked on my door one rainy Tuesday holding a jar of artichoke hearts she'd impulse-bought and had no idea what to do with. I had spinach wilting in the crisper and half a block of cream cheese that needed using. We stood in my kitchen, hungry and uninspired, until I remembered the dip from every potluck I'd ever attended. What if we just put it in a grilled cheese? Twenty minutes later, we were splitting two sandwiches that tasted like comfort food grew up and got interesting.

I made these for my brother during a weekend visit, and he ate his standing at the counter, eyes closed, declaring it better than any diner special he'd ever ordered. He asked for the recipe twice before he left. Now he texts me photos every few months of his own versions, each with some new twist he thought up. It's become our thing, this sandwich that started as a fridge cleanout experiment.

Ingredients

  • Shredded mozzarella cheese: It melts beautifully and provides that classic cheese pull without overpowering the other flavors, so use the pre-shredded kind or shred it yourself for better melt.
  • Cream cheese, softened: This is what makes the filling creamy and spreadable instead of clumpy, so leave it out on the counter for at least 30 minutes before mixing.
  • Grated Parmesan cheese: It adds a sharp, nutty depth that balances the mildness of mozzarella, and freshly grated is always better than the shelf-stable kind.
  • Unsalted butter, softened: Room temperature butter spreads evenly on the bread without tearing it, which means better browning and crispness.
  • Fresh spinach, chopped: Baby spinach works great here because it wilts fast and doesn't need stemming, but make sure you squeeze out the moisture after cooking.
  • Canned or jarred artichoke hearts, drained and chopped: The marinated kind can make things too tangy, so stick with water-packed or brined versions and chop them small for even distribution.
  • Small garlic clove, minced: One clove is enough to add warmth without making the filling taste like garlic bread, but mince it fine so no one bites into a chunk.
  • Sourdough bread: The tanginess of sourdough complements the richness of the filling, and its sturdy structure holds up to the moisture without getting soggy.
  • Salt: Just a pinch brings out the flavors in the vegetables and cheese without making the sandwich taste salty.
  • Freshly ground black pepper: A little pepper adds subtle heat and complexity that you'll miss if you skip it.
  • Red pepper flakes (optional): A tiny pinch gives the filling a gentle kick that makes it more interesting, but it's completely optional if you prefer it mild.

Instructions

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Wilt the spinach:
Add the chopped spinach to a medium skillet with just a splash of water over medium heat, stirring until it collapses into itself and turns bright green, about 1 to 2 minutes. Drain it well and press out as much liquid as you can with the back of a spoon or a paper towel.
Make the filling:
In a bowl, combine the drained spinach, chopped artichoke hearts, softened cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if using. Stir everything together until it looks like a chunky, creamy spread.
Assemble the sandwiches:
Spread half of the spinach artichoke mixture onto one slice of sourdough, pressing it all the way to the edges so every bite has filling. Top with another slice of bread and repeat with the remaining ingredients for the second sandwich.
Butter the bread:
Spread softened butter on the outside of each slice, covering the surface evenly so the bread toasts to a uniform golden color. Don't skip the edges or they'll stay pale and soft.
Grill the sandwiches:
Heat a large nonstick skillet or griddle over medium heat and place both sandwiches in the pan. Cook for 3 to 4 minutes on the first side, pressing gently with a spatula, until the bread turns deep golden and crisp, then flip and repeat on the other side until the cheese melts and oozes slightly at the seams.
Serve:
Remove the sandwiches from the heat, let them rest for a minute so the filling sets slightly, then slice each in half diagonally. Serve immediately while the cheese is still warm and stretchy.
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Spinach Artichoke Grilled Cheese sandwich stacked high, served beside a steaming bowl of tomato soup. Save
Spinach Artichoke Grilled Cheese sandwich stacked high, served beside a steaming bowl of tomato soup. | turbobaker.com

There was a night last winter when the power went out and I made these on a cast iron skillet over my gas stove by candlelight. My kid sat on the counter swinging her legs, watching the bread turn golden in the flickering light, and when we finally ate them wrapped in blankets on the couch, she said it felt like an adventure. I think about that every time I make them now, how a sandwich can turn an inconvenience into a memory.

Choosing Your Bread

Sourdough is my go-to because the slight tang plays so well with the creamy filling, but I've made this with everything from ciabatta to rye when that's what I had on hand. Thicker slices hold more filling but take longer to cook through, so adjust your heat and timing accordingly. Avoid anything too soft or it'll turn mushy under the weight of the mixture. Day-old bread actually works better than fresh because it's firmer and crisps up beautifully without absorbing too much butter.

Making It Ahead

The spinach artichoke mixture keeps in the fridge for up to three days, so I often make a double batch and have it ready for quick lunches. Just bring it to room temperature before spreading or it'll be too stiff and tear the bread. You can even assemble the sandwiches without buttering them, wrap them in parchment, and keep them in the fridge for a few hours before cooking. I wouldn't freeze the assembled sandwiches because the filling gets watery when thawed, but the mixture alone freezes fine for up to a month.

Serving Suggestions

These sandwiches are rich enough to stand alone, but I usually serve them with something bright and acidic to cut through the creaminess. A simple green salad with lemon vinaigrette, a handful of pickles, or a cup of tomato soup all work beautifully. Sometimes I'll add a few chips on the side just for crunch, or slice up some crisp apple for a sweet contrast.

  • Pair with a tangy tomato soup for dipping and that classic grilled cheese experience elevated.
  • Serve alongside a crisp arugula salad dressed with balsamic to balance the richness.
  • Add a handful of kettle chips or pickles on the plate for texture and a salty, vinegary counterpoint.
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Close-up of Spinach Artichoke Grilled Cheese showing crisp crust and vibrant green spinach artichoke filling. Save
Close-up of Spinach Artichoke Grilled Cheese showing crisp crust and vibrant green spinach artichoke filling. | turbobaker.com

This sandwich has become my answer to the question of what to make when I want something that feels special but don't have the energy for anything complicated. It's proof that sometimes the best meals come from throwing together what you have and trusting your instincts.

Recipe Questions & Answers

Can I make this ahead of time?

You can prepare the spinach-artichoke filling up to 2 days in advance and store it in an airtight container in the refrigerator. Assemble and cook the sandwiches fresh when ready to serve for the best texture and melted cheese.

What bread works best for this sandwich?

Sourdough bread is ideal due to its sturdy structure and tangy flavor that complements the creamy filling. Whole wheat, multigrain, or thick-cut white bread are excellent alternatives that provide good structure.

How do I prevent the bread from burning while the cheese melts?

Use medium heat rather than high heat, which allows the cheese to melt gradually while the bread toasts. Press gently with a spatula and cover the skillet with a lid if needed to trap heat and accelerate melting.

Can I add other ingredients to customize it?

Absolutely. Fresh basil, roasted red peppers, sun-dried tomatoes, or caramelized onions work wonderfully. You can also add crispy bacon or prosciutto for a non-vegetarian version.

What's the best way to drain the spinach and artichokes?

After sautéing spinach, press it gently with a paper towel to remove excess moisture. For canned artichokes, drain thoroughly and pat dry with paper towels to prevent a soggy filling.

Spinach Artichoke Grilled Cheese

Gourmet grilled cheese with creamy spinach and artichoke filling, melted mozzarella, and crispy golden sourdough. Ready in 25 minutes.

Prep Time
15 minutes
Time to Cook
10 minutes
Total Duration
25 minutes
Written by Justin Reed


Skill Level Easy

Cuisine American

Amount 2 Number of Servings

Diet Info Meat-Free

What You Need

Dairy

01 1 cup shredded mozzarella cheese
02 1/2 cup cream cheese, softened
03 1/4 cup grated Parmesan cheese
04 2 tablespoons unsalted butter, softened

Vegetables

01 1 cup fresh spinach, chopped
02 1/2 cup canned or jarred artichoke hearts, drained and chopped
03 1 small garlic clove, minced

Bread

01 4 slices sourdough bread

Seasonings

01 1/4 teaspoon salt
02 1/8 teaspoon freshly ground black pepper
03 Pinch of red pepper flakes, optional

How to Cook

Step 01

Prepare the spinach: In a medium skillet over medium heat, add spinach with a splash of water. Sauté for 1 to 2 minutes until wilted. Drain excess moisture thoroughly.

Step 02

Combine filling ingredients: In a mixing bowl, combine sautéed spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if using. Mix until well blended.

Step 03

Assemble sandwiches: Spread the spinach-artichoke mixture evenly onto two slices of sourdough bread. Top with the remaining two bread slices to form sandwiches.

Step 04

Butter the bread: Butter the exterior surfaces of all bread slices generously on both sandwiches.

Step 05

Cook the sandwiches: Heat a large nonstick skillet or griddle over medium heat. Place sandwiches in the skillet and cook for 3 to 4 minutes per side, pressing gently, until bread is golden brown and cheese is melted.

Step 06

Finish and serve: Remove from heat, slice each sandwich in half diagonally, and serve immediately.

What You'll Need

  • Medium skillet
  • Mixing bowl
  • Spatula
  • Nonstick skillet or griddle
  • Knife

Allergy Details

Double-check each ingredient for possible allergens and always check with your doctor if you're unsure.
  • Contains milk from cheese and butter
  • Contains wheat from sourdough bread
  • May contain traces of soy or tree nuts depending on bread and cheese brand sourcing

Nutrition Details (each serving)

Nutritional info is meant to guide, but it's not medical advice.
  • Calorie Count: 430
  • Fats: 24 g
  • Carbohydrates: 39 g
  • Proteins: 16 g